Skip to Content

  • Wait Times
  • Site Search

MidMichigan Health - Breast Health Assessment Icon

Take our FREE 5 minute breast health assessment to estimate your risk of developing breast cancer.

Breast Cancer

ALLIANCE A011203: A Randomized Phase II Trial of Tamoxifen Versus
Z-Endoxifen HCL in Postmenopausal Women with Metastatic Estrogen Receptor Positive, HER2 Negative Breast Cancer

This study is for patients who are post-menopausal with locally advanced or metastatic estrogen receptor positive, HER2 negative breast cancer that is no longer responding to aromatase inhibitors (anti-estrogen therapies).

Purpose

The purpose of this study is to compare the effects of using Z-Endoxifen HCL to using tamoxifen. Z-Endoxifen HCL could shrink cancer and prevent it from spreading, but it could also cause side effects. This study will allow the researchers to know whether this new approach is better, the same, or worse than the usual approach of using tamoxifen.

Patients will be followed for a maximum of 5 years after registration into the study.

*An additional core needle biopsy of the breast cancer tissue or site of metastatic disease is required.

Have Questions?

We can help, contact one of our program coordinators today.

Center for Women's Health; Kathleen Ludwig (989) 837-9070

MidMichigan Medical Center - Gratiot; Candy Bendon (989) 466-7253

Or email at
breast.health@midmichigan.org

Related Locations